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Furthermore, isoptin 40 mg is present and another quantity of the drug substance isoptin 80 mg, and also formulations prolonged release isoptin sr, with quantities of active substance, respectively 120 and 240 mg.

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ISOPTIN regularly reduces the total systemic resistance (afterload) against which the heart works both at rest and at a given level of exercise by dilating peripheral arterioles.

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Inhalation Anesthetics. Animal experiments have shown that inhalation anesthetics depress cardiovascular activity by decreasing the inward movement of calcium ions. When used concomitantly.inhalation anesthetics and calcium antagonists.such as verapamil.should each be titrated carefully to avoid excessive cardiovascular depression.

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